What You Need to Know About Multiple Myeloma and How to Diagnose It
By Sayed EL Assal
Some facts about this disease:
Malignant disorder of plasma cells
Peak incidence between 60-70 years
Rare under the age of 30
Males are affected more than females.
Pathogenesis:
-The tissues are infiltrated by proliferating cells.
-One type of abnormal immunoglobulins (paraprotein) usually IgG or IgA.
-This paraprotein may cause auto-immune manifestations.
-The paraprotein may coat the platelets and coagulation factors.
-Production [...]